GENERAL FEATURES OF INFLAMMATION
By definition
inflammation can be said as a natural response of the body that occurs when any
vascularised tissues of the body get infected with microbes or there is a part
of tissue that is experiencing any damage mostly necrosis.
Does it
mean that inflammation is a good thing for our body?
If inflammation
is a natural response to infection then why do we have anti-inflammatory drugs?
Well to
discuss or to know answers to these questions we have to know how an inflammatory response is triggered in our body.
What are the
steps that occur during the process?
Commonly in
lay and sometimes in medical terms to inflammation is deemed as a harmful reaction in the body but actually, it is a protective process that definitely
has some risk in some individuals. The inflammatory process in our body actually
helps to get rid of the microbes that might invade the tissues and it also helps
to get rid of the necrotic tissues that might have appeared due to the
infection or any other reason.
What part of the body takes part in
the process of inflammation when there is a microbe infection?
Naturally, our body has defense mediators that are
present in the blood and they are sequestered so they don’t do any damage to
normal tissues, they are- pathocytic leukocytes, cytokines, and proteins of the complement system and similarly, there are cells in tissues like macrophages that
are in a lookout for invaders.
How does the process of inflammation
start?
When there is an invasion of microbe or any kind of
change in any part of the tissue in our body like necrosis the macrophages present
in the tissue gets activated and thus
activates the mediators which recruit the leukocytes and plasma proteins. Which
then functions to kill the microbe or remove the unwanted substance. After the
inflammation, there is the repair of the tissue that underwent this process.
Then, what is the significance of inflammation, and why it is harmful in some cases?
Well if there was no process of inflammation in our
body the infections done by microbes would go unnoticed and would cause much
more damage, wounds would never heal as no inflammation would occur during
changes in any tissue and it might become dangerous at some point. On the
downside, depending on the individual the inflammation might trigger some autoimmune
pathways which can be dangerous like hypersensitivity, etc.
Conclusion
Inflammation is the first line process that occurs
during an infection or tissue damage and helps the body fight many infections. It
can also be harmful in some cases like autoimmune diseases and hypersensitivity
where should go see a doctor and might get some anti-inflammatory medicine
P.S stay healthy and safe and be informed. More on
inflammation soon J
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