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  Inflammatory reactions are triggered by a variety of stimuli and microbes and also by changes in the tissues:- Infections - the microbes like viruses, bacteria, fungi, and other microbes can induce an inflammatory reaction in the infected tissues, and this response is medically important. According to the type of the organism, the inflammation can be acute short-lived or systemic, or chronic. Actually, the inflammation process morphology can define the type of organism that is infected and sometimes even the etiology. Similarly, tissue necrosis and the presence of foreign bodies also induce inflammation; Immune reactions-  (also called hypersensitivity) are reactions in which the normally protective immune system damages the individual’s own tissues. The injurious immune responses may be directed against self-antigens, causing autoimmune diseases, or maybe inappropriate reactions against environmental substances, as in allergies, or against microbes. Conclusion- there are ma...

In the previous post , there was an insight into what is inflammation and its general introduction. In this one, we can know about what are the steps that occur in inflammation and what happens in those steps. Inducing of the inflammation in the host cell Any disturbing stimuli like the entry of any microbe or the onset of the necrosis of the tissues might activate the host cell or tissue mediators which induce inflammation by recruiting leukocytes and the complement proteins from the blood. The damage in any tissue or the entry of the microbes is sensed by the resident cells that are present in the tissue like macrophages, dendritic cells, mast cell, and many other types. These cells release mediators like the cytokines that recruit the plasma, leukocytes, and complement proteins. Fun fact- the accumulation of plasma in the tissue during inflammation by the mediators causes the edema of that region. The anti-inflammatory drugs are mostly the drugs that stop the mediator from recru...

  By definition inflammation can be said as a natural response of the body that occurs when any vascularised tissues of the body get infected with microbes or there is a part of tissue that is experiencing any damage mostly necrosis. Does it mean that inflammation is a good thing for our body? If inflammation is a natural response to infection then why do we have anti-inflammatory drugs? Well to discuss or to know answers to these questions we have to know how an inflammatory response is triggered in our body.   What are the steps that occur during the process? Commonly in lay and sometimes in medical terms to inflammation is deemed as a harmful reaction in the body but actually, it is a protective process that definitely has some risk in some individuals. The inflammatory process in our body actually helps to get rid of the microbes that might invade the tissues and it also helps to get rid of the necrotic tissues that might have appeared due to the infection or any...